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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFPQ All Species: 11.52
Human Site: Y602 Identified Species: 25.33
UniProt: P23246 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P23246 NP_005057.1 707 76149 Y602 E S Y S R M G Y M D P R E R D
Chimpanzee Pan troglodytes XP_524659 619 68740 E520 M Q L R Q E E E R R R R E E E
Rhesus Macaque Macaca mulatta XP_001088371 523 58669 R429 M G M N M N N R A T I P G P P
Dog Lupus familis XP_532566 663 71851 Y558 E S Y S R M G Y M D P R E R D
Cat Felis silvestris
Mouse Mus musculus Q8VIJ6 699 75423 Y594 E S Y S R M G Y M D P R E R D
Rat Rattus norvegicus Q4KLH4 522 58741 T430 M N M N N R G T I P G P P M G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513533 430 49120 N343 M G G G G A M N M G D P Y G S
Chicken Gallus gallus Q5ZK88 523 58452 T431 M N M N N R G T L P G P A M G
Frog Xenopus laevis NP_001080735 464 53169 R377 D A R E A D L R M A Q M A M P
Zebra Danio Brachydanio rerio Q1JPY8 512 57679 G425 M G M G G R V G A M G P D G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q04047 700 76958 E558 D N E R K K L E W E M R E K Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.5 45.5 84.3 N.A. 94 45.2 N.A. 59.2 45.1 40.5 42.1 N.A. 28.4 N.A. N.A. N.A.
Protein Similarity: 100 66.1 55.7 86.4 N.A. 95.1 56 N.A. 60.4 55.8 51 52.9 N.A. 41.5 N.A. N.A. N.A.
P-Site Identity: 100 13.3 0 100 N.A. 100 6.6 N.A. 6.6 6.6 6.6 0 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 6.6 100 N.A. 100 26.6 N.A. 6.6 26.6 20 6.6 N.A. 46.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 10 0 0 19 10 0 0 19 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 0 0 0 0 10 0 0 0 28 10 0 10 0 28 % D
% Glu: 28 0 10 10 0 10 10 19 0 10 0 0 46 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 28 10 19 19 0 46 10 0 10 28 0 10 19 19 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 10 10 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 10 0 0 0 19 0 10 0 0 0 0 0 0 % L
% Met: 55 0 37 0 10 28 10 0 46 10 10 10 0 28 0 % M
% Asn: 0 28 0 28 19 10 10 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 19 28 46 10 10 19 % P
% Gln: 0 10 0 0 10 0 0 0 0 0 10 0 0 0 10 % Q
% Arg: 0 0 10 19 28 28 0 19 10 10 10 46 0 28 0 % R
% Ser: 0 28 0 28 0 0 0 0 0 0 0 0 0 0 19 % S
% Thr: 0 0 0 0 0 0 0 19 0 10 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 28 0 0 0 0 28 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _